Research assistant (m/f/d) in the field of Immunological Research/Biotechnology

 

The Institute of Technical Chemistry (TCI) conducts biotechnological research in all its facets. Currently, around 100 academic staff - including Bachelor's and Master's students and (post)doctoral students - are involved in a large number of interdisciplinary and cross-sector research projects as well as collaborations with industrial partners.

The following position is to be filled at the TCI as soon as possible: Research assistant (m/f/d) in the field of Immunological Research/Biotechnology (salary scale 13 TV-L, 67 %)

The position is limited to 36 months and is part of a joint project with Hannover Medical School, Hannover University of Applied Sciences and Arts and two biotechnology companies in Lower Saxony entitled "HLA streptamers to improve diagnostics and individualised T cell therapy for polyomavirus infection after transplantation". The aim is to develop a methodology for T cell engineering in kidney transplant patients with polyomavirus nephropathy, which can lead to transplant failure. Prof. Dr Blume's working group (head of the consortium) is based at the TCI, which has a fully equipped cell culture laboratory at the NIFE (Lower Saxony Centre for Biomedical Engineering, Implant Research and Development) with access to various core facilities such as flow cytometry.

Your position at a glance

Your research task includes the development of a T-cell immunity test based on HLA streptamers for blood cells from healthy blood donors from the Institute of Transfusion Medicine and Transplantation Engineering at the MHH following (inapparent) polyomavirus nephropathy. These will later also be used in blood cells from immunocompromised patients at the Department of Nephrology at the MHH. You will be responsible for the development of a protocol for the isolation of virus-specific T cells. Furthermore, you will be the contact person for a collaboration with the University of Bielefeld, where a TCR scan will be performed with the HLA streptamers and a TCR library will be created. Your work will be based on the preliminary work of the Blume group in the field of T-cell cultivation, which will be supervised by an experienced member of staff. The possibility of a doctorate is given.

Who are we looking for?

The prerequisite for employment is a university degree (Master's or comparable degree) in a relevant discipline, e.g. biochemistry, chemistry, biotechnology, life science, human biology, biology. Comprehensive knowledge in the field of immunology and molecular biology is required

In addition, we expect the following qualifications:

• Very good knowledge of MS Office and molecular biology software such as Snap Gene
• Very good written and spoken English and German language skills for scientific presentations and the supervision of students are desirable

Leibniz University Hannover is committed to equal opportunities and diversity. The aim is to utilise everyone's potential and open up opportunities. We therefore welcome applications from all interested parties regardless of their gender, nationality, ethnic origin, religion or ideology, disability, age, sexual orientation and identity.

We strive for an equal distribution of employees and a reduction of underrepresentation in accordance with the Lower Saxony Equal Rights Act (NGG). We therefore particularly welcome applications for the above-mentioned position from women. People with a severe disability will be given preference if they have the same qualifications.

What do we offer?

With more than 5,000 employees, Leibniz University Hannover is one of the largest and most attractive employers in the Hannover region. We offer an exciting interdisciplinary and international working environment and promote personal and professional development ranging from (inter)disciplinary skills to leadership competences and languages.

Within the Institute of Technical Chemistry, but also at NIFE, you will meet open-minded and active employees with diverse horizons of experience who are motivated to plan and carry out joint social activities. As part of your work, you will have the opportunity to work in and consult with two biotechnology companies in Lower Saxony. You can take part in national and international conferences. A canteen close to the campus offers a wide range of options (e.g. vegan cuisine) and NIFE has excellent transport links.

 

Please send your application by 15.08.2024 with the usual documents and reference “development of a T-cell-immunity-test” in electronic form to